MEGGABIOTICS™ | About Us — A New Class of Oral Immunotherapy

About us

MEGGABIOTICS founded by John Hare — Building a new category in precision microbiome immunotherapy.

We are MEGGABIOTICS. For nearly three decades, our mission has been singular: to develop safe, scalable, non‑antibiotic biologics that prevent and treat disease at its source. Led by entrepreneur and lifelong builder John Hare, we’ve created a platform that redefines what’s possible—precision immunotherapy delivered orally, derived from eggs, and designed to work with the body, not against it.

We call this new category MEGGABIOTICS — a paradigm shift that bridges the gap between a safe food and pharmaceutical power. Today, we’re advancing phase 2 clinical trials for C. difficile, exploring prevention of hospital acquired infections, and opening doors to reversing chronic diseases rooted in the gut.

The Founder: John Hare

Entrepreneur. Builder. Competitor. John Hare’s journey started with a Bachelor of Science in Agriculture and an MBA, followed by early experience at the federal Department of Agriculture—where he gained deep insight into policy, regulation, and national food systems. After 18 months, the entrepreneurial pull proved too strong.

His first venture was a diversified manufacturing company employing 60 people, with capabilities in offset printing, plastic injection molding, chrome plating, zinc and aluminum die casting, and an in‑house tool and die shop. That experience forged his expertise in operations, scaling production, quality control, and team leadership—skills that would later prove essential in bringing a novel biologic to market.

He then acquired his family’s animal feed ingredient distribution business in Western Canada. But in 1997, a deeper calling emerged: developing IgY‑based oral antibody solutions to prevent and treat infection without the collateral damage of antibiotics. That work became his life’s focus, eventually giving rise to MEGGABIOTICS and the platform that now bears the same name.

“I’ve always believed in addressing root causes rather than symptoms—whether in manufacturing, policy, or medicine. MEGGABIOTICS is the culmination of that philosophy.”

Beyond business: John’s competitive drive extends far beyond the boardroom. He ran for Prime Minister of his elementary school (and won), later sought a provincial nomination, and in 1984 ran federally in Canada’s national election. Sports have been a constant: he played football and hockey from age 9, was part of the 1969 Canadian juvenile football championship team, and competed in rugby for 39 consecutive years—retiring at 64 as the oldest active player in the province. He still plays hockey three times a week and was part of the runner‑up team in the 2022 USA National Championship (70+ division). John is also an instrument-rated private pilot.

Married for 50 years, father of three, grandfather of two. His credo: “Still building. Still competing. Still learning.”

Our Mission: Rethinking Immunotherapy

At MEGGABIOTICS, we saw a gap in medicine: antibiotics are powerful but indiscriminate, decimating the gut microbiome and driving resistance. Probiotics and prebiotics offer support but lack precision. Vaccines are preventive but can’t treat active infection. We asked: what if we could deliver targeted immunotherapy orally, with the safety of food and the potency of a biologic?

That question led us to IgY antibodies—antibodies derived from hens immunized against specific pathogens. The result is a platform that acts directly in the gut, neutralizes harmful bacteria and viruses, and leaves the beneficial microbiome untouched. It’s precision immunotherapy, but oral, non‑systemic, and scalable.

Our focus is simple: address root causes, not symptoms. Whether it’s C. difficile in hospitals, E. coli in food safety, or chronic inflammation linked to gut dysbiosis—MEGGABIOTICS offers a fundamentally new way to intervene.
The Birth of MEGGABIOTICS

John Hare coined the term MEGGABIOTICS to give a name to this new category. It stands for: Microbiome + Egg + Antibodies + Biotics. The goal was to create a term as recognizable as antibiotics, probiotics, or vaccines—but one that reflects precision action inside the microbiome.

MEGGABIOTICS isn’t an antibiotic, probiotic, prebiotic, or vaccine—yet it can serve as a replacement or adjunct for all of them in specific applications. It works by delivering high‑concentration polyclonal antibodies directly to the gut, targeting only the pathogens causing trouble. Because it’s derived from eggs, its safety profile is essentially that of a food—the only known risk being egg allergy, which is rare and manageable.

A New Class
MEGGABIOTICS is being developed as both a FDA‑track drug (phase 2 for C. difficile) and a functional food, unlocking regulatory and commercial pathways that conventional biologics can’t access.
How MEGGABIOTICS Works
Egg‑Derived IgY

Hens are immunized against specific pathogens. The antibodies (IgY) are harvested from eggs, providing a high‑yield, scalable, and ethical source of targeted immunotherapy.

Precision Targeting

Each antibody is designed to bind to a specific pathogen—C. difficile, E. coli, rotavirus, etc.—neutralizing it without harming commensal bacteria.

Oral & Non‑Systemic

MEGGABIOTICS is ingested and acts locally in the gut lumen. It does not enter the bloodstream, avoiding systemic side effects and preserving the body’s natural defenses.

Safe as Food

Because the active ingredient is a food‑derived antibody, the safety profile is exceptional. No microbiome disruption, no resistance pressure—just targeted elimination.

Clinical Proof: C. Difficile

C. difficile infects nearly 500,000 Americans annually, with a mortality rate of 6–10%. Standard antibiotics (vancomycin, fidaxomicin) fail in 20–30% of cases. MEGGABIOTICS is changing that.

>90%
Treatment success in phase 2 clinical trials — surpassing the current standard of care

But treatment is only half the story. The real breakthrough is prevention. Patients on broad‑spectrum antibiotics become susceptible to C. diff for about a month. Daily oral MEGGABIOTICS during that window could prevent infection entirely — keeping patients safe, reducing hospital costs, and saving lives.

Prevention over reaction: “The ultimate goal should be, let’s take care of the patient first,” says Hare. “A preventive treatment for C. difficile would be first and foremost.” MEGGABIOTICS aims to become that first preventive.
Beyond Infection: Reversing Chronic Disease

Hippocrates said, “All disease begins in the gut.” Modern science confirms that gut dysbiosis underlies a wide range of chronic illnesses — asthma, arthritis, IBS, acid reflux, and even colorectal cancer and heart disease. Instead of managing symptoms for life, what if we could identify the specific bacterial overgrowth driving the condition and neutralize it?

Conventional Approach
  • Manage asthma with inhalers for decades
  • Treat arthritis with anti‑inflammatories
  • Suppress acid reflux with PPIs
  • Never ask “what caused this?”
MEGGABIOTICS Approach
  • Identify gut‑dwelling pathogen driving inflammation
  • Precision‑target with oral IgY antibodies
  • Restore microbiome balance
  • Reverse the chronic condition at its root

We’ve observed reversal of asthma, arthritis, acid reflux, and IBS in cases where specific gut bacteria were neutralized. The implications extend to colorectal cancer, cardiovascular disease, and other inflammatory conditions — all potentially linked to hidden microbial triggers.

The MEGGABIOTICS Platform
Acute Infections

C. difficile, ETEC, Salmonella, Rotavirus — rapid, targeted clearance without microbiome damage.

Prevention

Post‑antibiotic prophylaxis, hospital‑acquired infection prevention, rUTI, travel protection.

Chronic Conditions

Asthma, arthritis, IBS, acid reflux — reversing dysbiosis‑driven inflammation.

Emerging Frontiers

Colorectal cancer, cardiovascular disease, metabolic syndrome — where the gut may hold the key.

MEGGABIOTICS vs. Everything Else
Antibiotics

Disrupt microbiome, drive resistance, cause collateral damage. MEGGABIOTICS: no resistance pressure, spares good bacteria.

Probiotics / Prebiotics

General support, not targeted elimination. MEGGABIOTICS: precision strike against defined pathogens.

Vaccines

Prevention via immune training. MEGGABIOTICS: immediate neutralization; works as both treatment and prevention.

#NewCategory
MEGGABIOTICS is neither a drug nor a supplement — it’s a new biological class that straddles therapeutics and functional foods, opening pathways to rapid approval, scalable manufacturing, and global accessibility.

MEGGABIOTICS is more than a product — it’s a new lens on medicine. From saving lives from C. difficile to reversing chronic illness that has plagued patients for decades, the platform delivers on the promise of precision immunotherapy in an oral, affordable, and fundamentally safe form.

As John Hare puts it: “The ultimate goal should be, let’s take care of the patient first. MEGGABIOTICS does that — by going to the root.”

MEGGABIOTICS — advancing a new class of oral immunotherapy through clinical development and into a future where gut‑targeted precision medicine becomes standard of care.

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John Hare

Founder
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